Discover the body’s circadian rhythm

Marta - January 10, 2019 - Uncategorized /

Conventional medicine confirms the next wisdom of the East: The activity of individual organs and systems, hormone production and the absorption of medicines are strictly subject to circadian rhythms. His disorder can lie at the root of diabetes, trouble with pressure, and even tumors!

Research in scientific centres around the world confirms that people working at night are more likely to experience cardiovascular disease, digestive system disorders, diabetes, obesity, sleeping problems and chronic fatigue. Moreover, the World Health Organisation (WHO) and the International Agency for Research on Cancer (IARC) are reporting that they are more susceptible to certain types of cancers tumors, and shift work is one of the likely rakotwórczych1 factors.

Why these dependencies? Well, their cause is the lack of synchronization between the astronomical day-night cycle and the sleep-wake cycle and the rhythmic functions of the body. In other words, the human, individual organs and systems work according to the internal biological clock and operate smoothly only when the instructions are moving properly.

Rhythm of the Universe and the rhythm of the organism

Biological rhythms are one of the basic characteristics of life and mean the occurrence of periodic, foreseeable oscillations of physiological, biochemical and behavioural processes (see table). This internal clock was created as a result of evolution as an expression of adaptation of living organisms to regular changes occurring in the external environment. This means no less than that both of these rhythms are interconnected and the main generator of internal clock systems remain light and temperature stimuli coming from the outside, called Synchronizatorami2. If these signals do not appear within a certain period of time (as in the case of persons working in the night system), the biological clock is adjusted with all the consequences.

It is worth mentioning that although the rhythm of circadian, dependent on the supply of light and corresponding to the period of full rotation of the Earth, is of the utmost importance for the internal rhythm of the organism, there are also other units of time in which the oscillation occurs Individual processes. For example, the breathing cycle lasts approx. 4 s, contraction of the heart-1 s, and covering the REM phase and NREM Sleep Cycle-90 min. Bioeelektryczne changes in brain activity take place at 8-13 per second, and the hormonal cycle in women is a classic example of a monthly rhythm. And finally, some diseases are seasonal in nature (e.g. the so-called Winter depression), which proves the existence of an annual rhythm associated with the rotation of the earth around the sun.

An interesting unit of time is here week, unrelated to any phenomenon in the universe. Although its existence is a social contract, it is reflected in the change of well-being in individual dniach3. Moreover, acute cardiac incidents (including cases of sudden death in the course of arrhythmias) and other cardiovascular events occur most often on Mondays

What is responsible for the rhythm of the organism?

In animals and humans, the regulation of rhythms correspond to certain central nervous system structures, and in mammals the role of the upstream biological clock is played by the nadskrzyżowaniowe nucleus (SCN). These are structures located both on the anterior part of the hypothalamus, just above the intersection of the optic nerves. They are responsible for regulating the okołodobowych of physiological, biochemical and behawioralnych5 rhythms. Studies confirm that the destruction of these clusters of neurons causes the internal cycles of the organism to be adjusted.

On the one hand, the rytmika nuclei themselves are endogenous (independent of external factors), but on the other, they cannot function fully independently of the Nadskrzyżowaniowych. They are combined with the retinal ganglion cells of the eye, rich in melanopsynę (light-sensitive protein) and the pineal gland, an endocrine-producing prostate.

These ganglion cells send to SCN information about whether it is a day or night. Then the same message arrives at the pineal gland – the signal of a lack of light stimulates it to produce melatonin, which is secreted into the bloodstream, and the whole organism adjusts to the time of sleep (at night the lowest value reaches Body temperature, frequency and respiratory and blood pressure, and the number of cell divisions in the epidermis and regeneration processes in the liver are increasing) 6. This allows the endogenous rhythm to be adjusted to environmental conditions.

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